Functional Genomics & Systems Biology

Plenary Lecture

EC FP6 Proteome Binders: Alternatives to antibodies

11:00-11:10Chair / IntroductionDr. Michael Taussig, Head, Technology Research Group, The Babraham Institute, UK

11:10-11:35AnffibodiesDr. Per-Åke Nygren, Professor, Dept of Biotechnology, Royal Institute of Technology (KTH), Sweden

11:35-12:00AnkyrinsProf. Andreas Plückthun, Professor, Biochemistry Institute, Zurich University, Switzerland

12:00-12:20Aptamers, Biomarker Discovery, and DiagnosticsDr. Larry Gold, CEO & Chairman of the Board, SomaLogic Inc., USA

12:20-12:50ProteomeBinders: Towards a European Infrastructure of Affinity Reagents for Analysis of the Human ProteomeDr. Michael Taussig, Head, Technology Research Group, The Babraham Institute, UK

12:50-13:00Discussion & Conclusions 

Genome Technologies

15:00-15:10Chair / IntroductionDr. Jaume Bertranpetit, Professor, Dept. of Experimental & Health Sciences, Pompeu Fabra University, Spain

15:10-15:35Ultra High Throughput SequencingDr. Michael Egholm, Vice-President of R&D, 454 Life Sciences, Inc., USA

15:35-16:00Observing individual proteins and the partners they associate with in cells
and tissuesProf. Ulf Landegren, Professor of Molecular Medicine, Dept. of Genetics and Pathology, Rudbeck Laboratory, Uppsala, Sweden

16:00-16:25Microarray technology: new concepts, techniques and applicationsDr. Jörg Hoheisel, Head of Division of Functional Genome Analysis, German Cancer Research Centre (DKFZ), Germany

16:25-16:50Genomes, Proteomes, Single Cell AnalysisDr. Wilhelm Ansorge, ETH Lausanne, Switzerland

16:25-16:50Variation analysis and optimization of Aspergillus niger micro-array
analysisDr. Leo de Graaff, Wageningen University and Research Centre, The Netherlands

16:50-17:00Discussion & Conclusions

Plenary Lecture

Plenary Lecture

Human Atlas Projects - from RNA to proteins

11:00-11:10Chair/IntroductionDr. Mathias Uhlen, Professor of Microbiology, Royal Institute of Technology (KTH), Sweden

12:00-12:20Antibody-based Protein profiling in normal and Cancer TissuesProf. Sophia Hober, Professor, Dept. of Proteomics, Royal Institute of Technology (KTH), Sweden

11:35-12:00Canceromics: Genome-scale cancer biology - from gene to functionDr. Olli Kallioniemi, Professor VTT Technical Research Centre of Finland & University of Turku

11:10-11:30A quantitative chemical proteomics approach reveals novel modes of action of clinical ABL kinase inhibitorsDr. Bernhard Küster, Vice-President, Analytical Sciences & Informatics, Cellzome AG, Germany

12:25-12:50Flow cytometry-based analysis of promoter effects on solubility of recombinantly expressed proteinsMrs. Hanna Tegel, School of Biotechnology, Royal Institute of Technology (KTH), Sweden

12:50-13:00Discussion & Conclusions 

Comparative Genomics

15:00-15:10Chair / IntroductionProf. Svante Pääbo, Director, Dept. of Genetics, Max-Planck-Institute of Evolutionary Anthropology, Germany

15:10-15:30Whole genome shot-gun sequencing and comparative analysis of plant and animal genomesDr. Huanming Yang, Director & Professor, Beijing Genomics Institute (BGI), China

15:35-16:00Pathogenomics: Intracellular Pathogens Go ExtremeDr. Siv Andersson, Head of the Department of Evolution, Genomics and Systematics at the Evolutionary Biology Center at Uppsala University, Sweden

16:00-16:25Genetic dissection of trait loci in domestic animals reveals the significance of regulatory mutations in phenotypic evolutionProf. Leif Andersson, Professor in Functional Genomics, Uppsala University, Sweden

16:25-16:50Exploring Genomic Diversity of Lactococcus lactis by Comparative Genome Hybridisation with Multistrain DNA MicroarraysDr. Johan van Hylckama Vlieg, Principal Scientist Fermentation and Flavour, NIZO food research, The Netherlands

16:50-17:00Discussion & Conclusions

Plenary Lecture

Plenary Lecture

Nanobiotechnology

11:00-11:10Chair / IntroductionProf. Maria Garcia-Parajo, Group Leader BioNanophotonics, IBEC- Catalonian Institute for Bioengineering, Barcelona Scientific Park (PCB), Spain

11:10-11:35Nanotechnology applied in the life sciences: Molecular motors, protein chips, label free detection and communication with the nervous systemProf. Lars Montelius, Department of Physics & The Nanometer Structure Consortium, Lund University, Sweden

11:35-12:00From a Lab on a Chip to a Lab in a CellDr. Albert van den Berg, Group leader, BIOS/Lab-on-a-Chip group, University of Twente, MESA+ Institute for Nanotechnology, The Netherlands

12:00-12:25Biomolecular Motors at Work: From Cellular Function to NanotechnologyDr. Stefan Diez, Research Group Leader, Max-Planck-Institute of Molecular Cell Biology and Genetics, Germany

12:25-12:50Biosilicate and polymeric nanoparticulate solutions for biocatalysisDr. Paul Millner, Reader in Biotechnology, University of Leeds, UK

12:50-13:00Discussion & Conclusions 

Systems & Synthetic Biology

15:00-15:10Chair/IntroductionDr. Alfonso Valencia, Spanish Nacional Cancer Research Center, Spain

15:10-15:35Prof. Luis Serrano, Barcelona Biomedical Research Park, Spain

15:35-16:00Towards in vitro multi-step chemistryDr. Sven Panke, Bioprocess Laboratory, ETH Zurich, Switzerland

16:00-16:25Loosely coupled bioinformatics workflows for systems biologyProf. Douglas Kell, Professor of Chemistry & Director, Manchester Centre for Integrative Systems Biology, University of Manchester UK

16:25-16:50Transcriptional and Metabolic Response of Saccharomyces Cerevisiae to a Nutritional Perturbation when under stressDuygu Dikicioglu, Bogazici University, Turkey

16:50-17:00Discussion & Conclusions

Plenary Lecture